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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
5.76
Human Site:
S59
Identified Species:
8.44
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
S59
I
D
R
H
I
S
E
S
C
P
F
P
S
P
G
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
S59
T
D
R
H
I
S
K
S
C
P
F
P
S
P
G
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
Dog
Lupus familis
XP_537128
620
68704
P60
A
D
R
C
S
A
E
P
C
P
F
P
S
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
A59
T
A
D
K
P
G
H
A
S
S
T
N
S
P
S
Rat
Rattus norvegicus
Q66HG7
589
65047
A59
T
A
D
R
P
G
S
A
S
S
T
S
S
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
D54
Q
E
S
L
G
S
K
D
S
V
C
T
P
G
G
Chicken
Gallus gallus
XP_422189
625
69278
E64
N
E
V
V
Q
H
T
E
P
V
T
A
P
S
D
Frog
Xenopus laevis
NP_001106297
254
27959
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
D97
K
E
K
P
E
N
G
D
Q
T
A
D
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
D78
G
Y
R
G
G
N
R
D
G
G
G
F
H
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
T80
L
V
R
R
G
I
Q
T
T
A
P
K
T
K
K
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
C39
G
E
P
I
C
V
V
C
G
R
Y
G
E
Y
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
Q21
V
K
Q
K
S
I
D
Q
R
A
P
L
S
G
E
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
R58
V
T
G
G
D
F
F
R
R
A
G
R
Q
T
G
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
N86
H
N
H
N
P
Q
R
N
I
P
T
G
P
K
A
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
86.6
0
53.3
N.A.
13.3
13.3
N.A.
13.3
0
0
0
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
0
60
N.A.
20
20
N.A.
26.6
6.6
0
20
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
0
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
13.3
N.A.
N.A.
26.6
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
0
0
0
7
0
13
0
19
7
7
0
0
13
% A
% Cys:
0
0
0
7
7
0
0
7
19
0
7
0
0
0
0
% C
% Asp:
0
19
13
0
7
0
7
19
0
0
0
7
0
0
7
% D
% Glu:
0
25
0
0
7
0
13
7
0
0
0
0
7
0
7
% E
% Phe:
0
0
0
0
0
7
7
0
0
0
19
7
0
0
0
% F
% Gly:
13
0
7
13
19
13
7
0
13
7
13
13
0
19
32
% G
% His:
7
0
7
13
0
7
7
0
0
0
0
0
7
0
0
% H
% Ile:
7
0
0
7
13
13
0
0
7
0
0
0
0
0
7
% I
% Lys:
7
7
7
13
0
0
13
0
0
0
0
7
7
19
13
% K
% Leu:
7
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
7
0
13
0
7
0
0
0
7
0
0
0
% N
% Pro:
0
0
7
7
19
0
0
7
7
25
13
19
19
25
0
% P
% Gln:
7
0
7
0
7
7
7
7
7
0
0
0
7
0
0
% Q
% Arg:
0
0
32
13
0
0
13
7
13
7
0
7
0
0
0
% R
% Ser:
0
0
7
0
13
19
7
13
19
13
0
7
38
7
13
% S
% Thr:
19
7
0
0
0
0
7
7
7
7
25
7
7
13
0
% T
% Val:
13
7
7
7
0
7
7
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _